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Thorne Research Methyl-Guard Plus Capsules CBD * Boron is definitely notThorne Research Methyl Guard Plus It can be a very difficult task to get the right amount of nutrients for methylation even with a healthy diet. Luckily, theres no need to worry about that when you have Thorne Research Methyl Guard Plus, a supplement designed to promote healthy DNA methylation.* What is methylation? How does it help you? Methylation is when a methyl group is added to the cytosine in your DNA. Methylation levels peak when youre an